BDBM50311750 CHEMBL1076210::N-(2,6-dimethylbenzyl)-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-7-amine

SMILES Cc1[nH]c2c(NCc3c(C)cccc3C)nccc2c1C

InChI Key InChIKey=YIIXUMVWJVOYNW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311750   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311750(CHEMBL1076210 | N-(2,6-dimethylbenzyl)-2,3-dimethy...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of CYP3A4 using 7-benzyloxyquinoline substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311750(CHEMBL1076210 | N-(2,6-dimethylbenzyl)-2,3-dimethy...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311750(CHEMBL1076210 | N-(2,6-dimethylbenzyl)-2,3-dimethy...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311750(CHEMBL1076210 | N-(2,6-dimethylbenzyl)-2,3-dimethy...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50311750(CHEMBL1076210 | N-(2,6-dimethylbenzyl)-2,3-dimethy...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed