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BDBM50312101 CHEMBL1076408::N-(3-(3-fluorobenzamido)phenyl)-2-methoxybenzamide

SMILES: COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(F)c2)c1

InChI Key: InChIKey=PXIXFRQOZKDTCC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312101   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM50312101
PNG
(CHEMBL1076408 | N-(3-(3-fluorobenzamido)phenyl)-2-...)
Show SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(F)c2)c1
Show InChI InChI=1S/C21H17FN2O3/c1-27-19-11-3-2-10-18(19)21(26)24-17-9-5-8-16(13-17)23-20(25)14-6-4-7-15(22)12-14/h2-13H,1H3,(H,23,25)(H,24,26)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 6.48E+3n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium flux


Bioorg Med Chem Lett 19: 6502-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.059
BindingDB Entry DOI: 10.7270/Q2JD4WZJ
More data for this
Ligand-Target Pair