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BDBM50312513 CHEMBL1085913::[10-(4-Dimethylamino-benzyl)-3,4-dioxo-3,4-dihydro-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-2-yl]-acetic acid

SMILES: CN(C)c1ccc(Cn2c3ccccc3n3c2nn(CC(O)=O)c(=O)c3=O)cc1

InChI Key: InChIKey=IESARKBXKZMSEB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312513   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Rattus norvegicus)
BDBM50312513
PNG
(CHEMBL1085913 | [10-(4-Dimethylamino-benzyl)-3,4-d...)
Show SMILES CN(C)c1ccc(Cn2c3ccccc3n3c2nn(CC(O)=O)c(=O)c3=O)cc1
Show InChI InChI=1S/C20H19N5O4/c1-22(2)14-9-7-13(8-10-14)11-23-15-5-3-4-6-16(15)25-19(29)18(28)24(12-17(26)27)21-20(23)25/h3-10H,11-12H2,1-2H3,(H,26,27)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 3.84E+4n/an/an/an/an/an/a



Institute of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Inhibition of Albino rat eye lens ALR2 assessed as NADPH oxidation by spectrophotometry


Eur J Med Chem 45: 909-14 (2010)


Article DOI: 10.1016/j.ejmech.2009.11.031
BindingDB Entry DOI: 10.7270/Q2474B0X
More data for this
Ligand-Target Pair