BDBM50312525 (2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol::1-deoxy-L-idonojirimycin::CHEMBL175901::L-ido-1-Deoxynojirimycin

SMILES OC[C@@H]1NC[C@H](O)[C@@H](O)[C@@H]1O

InChI Key InChIKey=LXBIFEVIBLOUGU-UNTFVMJOSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50312525   

TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of sucrase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of GCS by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLactase/phlorizin hydrolase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of lactase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of rat intestinal isomaltase using p-nitrophenyl glycoside as substrate assessed as release of p-nitrophenol measured by spectrometric ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen debranching enzyme(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of glycogen glycogen de-branching enzyme by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of maltase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of rat intestinal sucrase using p-nitrophenyl glycoside as substrate assessed as release of p-nitrophenol measured by spectrometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312525((2S,3R,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-tri...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed