BDBM50312651 1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone::CHEMBL1083499::RWJ-671818

SMILES: [#6]-c1cnc(-[#7]-[#6]C(F)(F)c2ccccc2)c(=O)n1-[#6]-[#6](=O)-[#7]-[#6]-[#6]-[#8]\[#7]=[#6](\[#7])-[#7]

InChI Key: InChIKey=BWZFWTBHSZJRKG-UHFFFAOYSA-N

Data: 9 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50312651   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tissue-type plasminogen activator (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor VII (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Urokinase-type plasminogen activator (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin G (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil elastase (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Chymase (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasminogen (Human)	BDBM50312651 (RWJ-671818 | 1-{N-[2-(Amidinoaminooxy)ethyl]amino}...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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