BDBM50312778 (S)-(4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2'-fluorobiphenyl-4-yl)methanone::CHEMBL1080389
SMILES C[C@H]1CN(CCN1C(=O)c1ccc2cc[nH]c2c1)C(=O)c1ccc(cc1)-c1ccccc1F
InChI Key InChIKey=MESZSUFNQDICOD-SFHVURJKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50312778
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of muscarinic M3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of histamine H2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of dopamine D2 rceptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of 5HT2A (receptor)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of 5HT2C (receptor)More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of alpha2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of dopamine D3 rceptorMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of rat GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash luminescence a...More data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Antagonist activity at human GHSR expressed in CHOK1 cells assessed as inhibition of ghrelin-induced intracellular calcium flux by aequorin flash lum...More data for this Ligand-Target Pair