BDBM50312869 4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol::CHEMBL1076555::N-aryl-4-aryl-1,3-thiazole-2-amine, 5

SMILES: Oc1ccc(Nc2nc(cs2)-c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=ZFGXZJKLOFCECI-UHFFFAOYSA-N

Data: 24 KI  12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 50312869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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Transitional endoplasmic reticulum ATPase (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-amylase 1A (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingolipid delta(4)-desaturase DES1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 1 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Mouse)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine kinase 2 (Human)	BDBM50312869 (N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair