BDBM50313355 2-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)-3-methylphenylsulfonamido)acetic acid::CHEMBL1080384::US9150519, 1-61

SMILES Cc1cc(ccc1NC(=O)c1cc(ncn1)N(CC1CC1)C1CCCCC1)S(=O)(=O)NCC(O)=O

InChI Key InChIKey=RPSCCGWFQDERCL-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313355   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM50313355(2-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimi...)
Affinity DataEC50:  12nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM50313355(2-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimi...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Serono

US Patent
LigandPNGBDBM50313355(2-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimi...)
Affinity DataEC50:  259nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails US Patent