BDBM50313465 4-(4-chloro-3-(trifluoromethyl)phenyl)-6-propylpyrimidine-2-carbonitrile::CHEMBL1079100

SMILES CCCc1cc(nc(n1)C#N)-c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=AKJKYYDGUADZBI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50313465   

TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313465(4-(4-chloro-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313465(4-(4-chloro-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313465(4-(4-chloro-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313465(4-(4-chloro-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313465(4-(4-chloro-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313465(4-(4-chloro-3-(trifluoromethyl)phenyl)-6-propylpyr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed