BDBM50313478 4-(3-(tert-butylamino)propyl)-6-(3-(trifluoromethyl)phenyl)pyrimidine-2-carbonitrile::CHEMBL1084402

SMILES: CC(C)(C)NCCCc1cc(nc(n1)C#N)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=ADOJZMMSYUTJST-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50313478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Human)	BDBM50313478 (4-(3-(tert-butylamino)propyl)-6-(3-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50313478 (4-(3-(tert-butylamino)propyl)-6-(3-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM50313478 (4-(3-(tert-butylamino)propyl)-6-(3-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin B (Human)	BDBM50313478 (4-(3-(tert-butylamino)propyl)-6-(3-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50313478 (4-(3-(tert-butylamino)propyl)-6-(3-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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