BDBM50313640 CHEMBL1079113::N-(4-methyl-3-(4-(6-methylpyridin-3-yl)pyrimidin-2-ylamino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide

SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3ccc(C)nc3)c2)CC1

InChI Key InChIKey=AFMXVBAHMGWYAZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313640   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313640(CHEMBL1079113 | N-(4-methyl-3-(4-(6-methylpyridin-...)
Affinity DataIC50:  43nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313640(CHEMBL1079113 | N-(4-methyl-3-(4-(6-methylpyridin-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of wild type Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed