BDBM50313644 (E)-3-(2-(6-(cyclopropylamino)-7H-purin-9(8H)-yl)vinyl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide::CHEMBL1077317

SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(\C=C\N3CNc4c3ncnc4NC3CC3)c2)cc(c1)C(F)(F)F

InChI Key InChIKey=BNIPBKFCGMYCDD-BQYQJAHWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313644   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313644((E)-3-(2-(6-(cyclopropylamino)-7H-purin-9(8H)-yl)v...)
Affinity DataIC50:  25nMAssay Description:Inhibition of wild type AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313644((E)-3-(2-(6-(cyclopropylamino)-7H-purin-9(8H)-yl)v...)
Affinity DataIC50:  8nMAssay Description:Inhibition of wild type Bcr-AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed