BDBM50313645 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1081312

SMILES: Nc1ncnc2n(nc(-c3cnc4[nH]ccc4c3)c12)C1CCCC1

InChI Key: InChIKey=NVRXTLZYXZNATH-UHFFFAOYSA-N

Data: 10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50313645   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase ATR (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Serine/threonine-protein kinase mTOR (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Target of rapamycin complex subunit LST8 (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Target of rapamycin complex subunit LST8 (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Breakpoint cluster region protein/Tyrosine-protein kinase ABL1 (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50313645 (1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair