BDBM50313648 CHEMBL2374458::trans-3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-6-yl)-1-(4-(1-methylpiperidin-4-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES COc1ccccc1Cc1nc2ccc(cc2[nH]1)-c1nn([C@H]2CC[C@@H](CC2)C2CCN(C)CC2)c2ncnc(N)c12

InChI Key InChIKey=OBDZFXLPCBGQSA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313648   

TargetEpidermal growth factor receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313648(trans-3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-6...)
Affinity DataIC50: 81nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313648(trans-3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-6...)
Affinity DataIC50: 81nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50313648(trans-3-(2-(2-methoxybenzyl)-1H-benzo[d]imidazol-6...)
Affinity DataIC50: 81nMAssay Description:Inhibition of erbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed