BDBM50313661 CHEMBL1095040::N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide::N-(6-chloro-5-phenyl-1H-indazol-3-yl)butyramide

SMILES CCCC(=O)Nc1n[nH]c2cc(Cl)c(cc12)-c1ccccc1

InChI Key InChIKey=WGVVIVGNBSSANI-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50313661   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Rattus norvegicus)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Tau phosphorylation in rat cerebral cortex after 120 mins by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed