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BDBM50313688 CHEMBL1085920::N-(6-(6-hydroxypyridin-3-yl)-1H-indazol-3-yl)butyramide

SMILES: CCCC(=O)Nc1[nH]nc2cc(ccc12)-c1ccc(=O)[nH]c1

InChI Key: InChIKey=UUXLQKKBOYQWIZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313688   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50313688
PNG
(CHEMBL1085920 | N-(6-(6-hydroxypyridin-3-yl)-1H-in...)
Show SMILES CCCC(=O)Nc1[nH]nc2cc(ccc12)-c1ccc(=O)[nH]c1
Show InChI InChI=1S/C16H16N4O2/c1-2-3-15(22)18-16-12-6-4-10(8-13(12)19-20-16)11-5-7-14(21)17-9-11/h4-9H,2-3H2,1H3,(H,17,21)(H2,18,19,20,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.68E+4n/an/an/an/an/an/a



Sanofi-Aventis

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assay


Bioorg Med Chem Lett 20: 1985-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.114
BindingDB Entry DOI: 10.7270/Q2QN66XJ
More data for this
Ligand-Target Pair