BDBM50313751 4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid::4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylicacid::4'-(2-(5-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid::CHEMBL1089721

SMILES CCC(C)(C)Cc1cnc(CCc2ccc(cc2)-c2ccccc2C(O)=O)[nH]1

InChI Key InChIKey=AXHVEQQLKVIZLO-UHFFFAOYSA-N

Data  2 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50313751   

TargetBombesin receptor subtype-3(Mus musculus)
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataEC50:  9.60nMAssay Description:Agonist activity at mouse BRS3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataIC50:  11nMAssay Description:Binding affinity to human BRS3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human BRS3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]D-Tyr6-betaAla11-Phe13-Nle14-bombesin from human BRS-3 expressed in NFAT-CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Mus musculus)
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataEC50:  9.60nMAssay Description:Agonistic activity at mouse BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataEC50:  101nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assay relative to D-Tyr6-betaAla1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Mus musculus)
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataEC50:  9.60nMAssay Description:Agonist activity at mouse BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Mus musculus)
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at mouse BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assay relative to D-Tyr6-betaAla1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataEC50:  25nMAssay Description:Agonistic activity at human BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM50313751(4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethy...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed