BDBM50313852 8-(2,4-dichlorophenyl)-N-(1,3-dimethoxypropan-2-yl)-2,7-dimethyl-3,4-dihydropyrazolo[1,5-a][1,3,5]triazin-4-amine::CHEMBL1091818

SMILES COCC(COC)NC1N=C(C)Nc2c(c(C)nn12)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=ZKZULFXLHWYLCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313852   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50313852(8-(2,4-dichlorophenyl)-N-(1,3-dimethoxypropan-2-yl...)
Affinity DataIC50: 2.90nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed