BDBM50313920 CHEMBL1085444::N-(4-(2-((R)-2-hydroxy-2-(pyridin-3-yl)ethylamino)ethyl)phenyl)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide

SMILES O[C@@H](CNCCc1ccc(NC(=O)CN2CC(CC2=O)c2ccccc2)cc1)c1cccnc1

InChI Key InChIKey=RTSLMYXQERUVCS-YNMFNDETSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313920   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313920(CHEMBL1085444 | N-(4-(2-((R)-2-hydroxy-2-(pyridin-...)
Affinity DataIC50:  6.70E+3nMAssay Description:Displacement of [125I]cyanopindolol from human beta 2 adrenergic receptor expressed in CHO cells at 10 uM after 3 to 4 hrs by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313920(CHEMBL1085444 | N-(4-(2-((R)-2-hydroxy-2-(pyridin-...)
Affinity DataIC50:  1.40E+3nMAssay Description:Displacement of [125I]cyanopindolol from human beta 1 adrenergic receptor expressed in CHO cells at 10 uM after 3 to 4 hrs by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313920(CHEMBL1085444 | N-(4-(2-((R)-2-hydroxy-2-(pyridin-...)
Affinity DataEC50:  64nMAssay Description:Agonistic activity at human beta3 adrenergic receptor expressed in CHO cells assessed as amount of cAMP released after 1 hr by fluorescence resonance...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed