BDBM50313935 (R)-2-(2-aminothiazol-4-yl)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)ethyl)phenyl)acetamide::CHEMBL1090425

SMILES Nc1nc(CC(=O)Nc2ccc(CCNC[C@H](O)c3cccnc3)cc2)cs1

InChI Key InChIKey=OGIIQRCJSHVATM-SFHVURJKSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50313935   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313935((R)-2-(2-aminothiazol-4-yl)-N-(4-(2-(2-hydroxy-2-(...)
Affinity DataIC50:  8.70E+3nMAssay Description:Displacement of [125I]cyanopindolol from human beta 2 adrenergic receptor expressed in CHO cells at 10 uM after 3 to 4 hrs by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313935((R)-2-(2-aminothiazol-4-yl)-N-(4-(2-(2-hydroxy-2-(...)
Affinity DataIC50:  8.30E+3nMAssay Description:Displacement of [125I]cyanopindolol from human beta 1 adrenergic receptor expressed in CHO cells at 10 uM after 3 to 4 hrs by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50313935((R)-2-(2-aminothiazol-4-yl)-N-(4-(2-(2-hydroxy-2-(...)
Affinity DataEC50:  6.80nMAssay Description:Agonistic activity at human beta3 adrenergic receptor expressed in CHO cells assessed as amount of cAMP released after 1 hr by fluorescence resonance...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed