BindingDB logo
myBDB logout

BDBM50314001 8-mesityl-2-methyl-3-(morpholine-4-carbonyl)-5,6-dihydroimidazo[1,2-a]pyrimidin-7(8H)-one::CHEMBL1088326

SMILES: Cc1nc2N(C(=O)CCn2c1C(=O)N1CCOCC1)c1c(C)cc(C)cc1C

InChI Key: InChIKey=SOHFBZYTLOBPAW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314001   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50314001
PNG
(8-mesityl-2-methyl-3-(morpholine-4-carbonyl)-5,6-d...)
Show SMILES Cc1nc2N(C(=O)CCn2c1C(=O)N1CCOCC1)c1c(C)cc(C)cc1C
Show InChI InChI=1S/C21H26N4O3/c1-13-11-14(2)18(15(3)12-13)25-17(26)5-6-24-19(16(4)22-21(24)25)20(27)23-7-9-28-10-8-23/h11-12H,5-10H2,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>5.00E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Research & Development

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr-o-CRF from human CRFR1 expressed in human IMR32 cells


Bioorg Med Chem Lett 20: 1905-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.127
BindingDB Entry DOI: 10.7270/Q24Q7V3F
More data for this
Ligand-Target Pair