BDBM50314073 3-(3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide::3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide::CHEMBL1088751::D3RKN_8::PH-797804::PHA-797804

SMILES: Cc1ccc(cc1N2C(=CC(=C(C2=O)Br)OCc3ccc(cc3F)F)C)C(=O)NC

InChI Key: InChIKey=KCAJXIDMCNPGHZ-UHFFFAOYSA-N

Data: 4 KI  7 IC50  4 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50314073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Human)	BDBM50314073 (3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair