BDBM50314198 (+/-)-1-(4-(2-(5-(1-(2-hydroxy-3-(piperidin-1-yl)propyl)-5-(methylsulfonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-2-(trifluoromethyl)phenylthio)ethyl)piperazin-1-yl)ethanone::CHEMBL1089293
SMILES CC(=O)N1CCN(CCSc2cc(ccc2C(F)(F)F)-c2nn(CC(O)CN3CCCCC3)c3CCN(Cc23)S(C)(=O)=O)CC1
InChI Key InChIKey=ICPBGKIKHDNXQD-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50314198
TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development LLC
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development LLC
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human cathepsin S by ADAM-28 substrate-based fluorescence assayMore data for this Ligand-Target Pair