BDBM50314368 4-hydroxy-2-((4-(4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)piperidin-1-yl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1093754

SMILES Cn1cc(\C=C2/Oc3cccc(O)c3C2=O)c2c(ccnc12)N1CCC(CC1)C(=O)N1CCN(CCO)CC1

InChI Key InChIKey=LRWLSMIVBWZTPN-ULJHMMPZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314368   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314368(4-hydroxy-2-((4-(4-(4-(2-hydroxyethyl)piperazine-1...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50314368(4-hydroxy-2-((4-(4-(4-(2-hydroxyethyl)piperazine-1...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed