BindingDB logo
myBDB logout

BDBM50314523 CHEMBL1091770::N-ethyl-N-(6-methoxypyridin-3-yl)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carboxamide

SMILES: CCN(C(=O)c1ccc([nH]c1=O)-c1ccccc1)c1ccc(OC)nc1

InChI Key: InChIKey=UIBHNPAXZOZMPF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314523   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oxytocin receptor


(Homo sapiens (Human))
BDBM50314523
PNG
(CHEMBL1091770 | N-ethyl-N-(6-methoxypyridin-3-yl)-...)
Show SMILES CCN(C(=O)c1ccc([nH]c1=O)-c1ccccc1)c1ccc(OC)nc1
Show InChI InChI=1S/C20H19N3O3/c1-3-23(15-9-12-18(26-2)21-13-15)20(25)16-10-11-17(22-19(16)24)14-7-5-4-6-8-14/h4-13H,3H2,1-2H3,(H,22,24)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
97n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human cloned OT receptor by cell based beta-lactamase reporter gene assay


Bioorg Med Chem Lett 20: 2224-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.018
BindingDB Entry DOI: 10.7270/Q2X34XMS
More data for this
Ligand-Target Pair