BDBM50314644 3-amino-N-cyclopropyl-2-(4-(3-(2,6-dichloro-4-methylphenoxy)propyl)benzyl)-N-(2,3-dichlorobenzyl)propanamide::CHEMBL1092186

SMILES Cc1cc(Cl)c(OCCCc2ccc(CC(CN)C(=O)N(Cc3cccc(Cl)c3Cl)C3CC3)cc2)c(Cl)c1

InChI Key InChIKey=HHFNUPNPOFOJPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314644   

TargetRenin(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50314644(3-amino-N-cyclopropyl-2-(4-(3-(2,6-dichloro-4-meth...)
Affinity DataIC50:  0.400nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50314644(3-amino-N-cyclopropyl-2-(4-(3-(2,6-dichloro-4-meth...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant renin in human citrated-plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed