BDBM50314682 (R)-2-(2-naphthamido)-3-(3-(trifluoromethyl)phenyl)propanoic acid::CHEMBL1091805

SMILES OC(=O)[C@@H](Cc1cccc(c1)C(F)(F)F)NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=BFGGKKPGABBYSG-GOSISDBHSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314682   

TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314682((R)-2-(2-naphthamido)-3-(3-(trifluoromethyl)phenyl...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314682((R)-2-(2-naphthamido)-3-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human Pin1 by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed