BDBM50314811 2-((4-(2-(2-(4-chlorophenyl)-5-methyloxazol-4-yl)ethoxy)benzyl)(ptolyloxycarbonyl)amino)acetic acid::CHEMBL1089176

SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)C(=O)Oc2ccc(C)cc2)cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=QNBMJPHGJSBCGA-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50314811   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50314811(2-((4-(2-(2-(4-chlorophenyl)-5-methyloxazol-4-yl)e...)
Affinity DataIC50:  942nMAssay Description:Binding affinity to human His-tagged PPARalpha LBD (E196-Y468) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50314811(2-((4-(2-(2-(4-chlorophenyl)-5-methyloxazol-4-yl)e...)
Affinity DataEC50:  75.4nMAssay Description:Agonist activity at human PPARgamma LBD (176-477) expressed in HEK293 cells coexpressing GAL4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50314811(2-((4-(2-(2-(4-chlorophenyl)-5-methyloxazol-4-yl)e...)
Affinity DataIC50:  141nMAssay Description:Binding affinity to human His-tagged PPARgamma LBD (Q203-Y477) expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50314811(2-((4-(2-(2-(4-chlorophenyl)-5-methyloxazol-4-yl)e...)
Affinity DataEC50:  289nMAssay Description:Agonist activity at human PPARalpha LBD (167-468) expressed in HEK293 cells coexpressing GAL4-DBD by transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed