BDBM50314995 2-(2-amino-6-((2-(2-chlorophenyl)-5-(4-(pentyloxy)phenyl)-1H-pyrrol-1-yl)methyl)pyridin-3-ylamino)ethanol::CHEMBL1089186

SMILES CCCCCOc1ccc(cc1)-c1ccc(-c2ccccc2Cl)n1Cc1ccc(NCCO)c(N)n1

InChI Key InChIKey=JUOGTZUVNDFPCE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314995   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50314995(2-(2-amino-6-((2-(2-chlorophenyl)-5-(4-(pentyloxy)...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant BACE1 expressed CHO cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50314995(2-(2-amino-6-((2-(2-chlorophenyl)-5-(4-(pentyloxy)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50314995(2-(2-amino-6-((2-(2-chlorophenyl)-5-(4-(pentyloxy)...)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed