BDBM50315006 6-((2-(2-chlorophenyl)-5-(4-methoxyphenyl)-1H-pyrrol-1-yl)methyl)pyridin-2-amine::CHEMBL1093152

SMILES COc1ccc(cc1)-c1ccc(-c2ccccc2Cl)n1Cc1cccc(N)n1

InChI Key InChIKey=YCLYXZNWHAWIQN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315006   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50315006(6-((2-(2-chlorophenyl)-5-(4-methoxyphenyl)-1H-pyrr...)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth

Curated by ChEMBL
LigandPNGBDBM50315006(6-((2-(2-chlorophenyl)-5-(4-methoxyphenyl)-1H-pyrr...)
Affinity DataIC50:  2.45E+3nMAssay Description:Inhibition of human recombinant BACE1 expressed CHO cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed