BDBM50315231 4-(2,6-difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine::8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1H-pyrazol-4-yl)quinoxaline::CHEMBL1092926

SMILES: Fc1cc(cc(F)c1CN1CCOCC1)-c1cccc2ncc(nc12)-c1cnn(c1)C1CCNCC1

InChI Key: InChIKey=IBPVXAOOVUAOKJ-UHFFFAOYSA-N

Data: 11 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50315231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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Non-receptor tyrosine-protein kinase TYK2 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	384	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	303	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM50315231 (8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair