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BDBM50315329 1-(8-chlorobenzofuro[3,2-d]pyrimidin-4-yl)-N-methylpiperidin-4-amine::CHEMBL1091567

SMILES: CNC1CCN(CC1)c1ncnc2c3cc(Cl)ccc3oc12

InChI Key: InChIKey=NAUNZRHUJRAJFD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315329   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50315329
PNG
(1-(8-chlorobenzofuro[3,2-d]pyrimidin-4-yl)-N-methy...)
Show SMILES CNC1CCN(CC1)c1ncnc2c3cc(Cl)ccc3oc12
Show InChI InChI=1S/C16H17ClN4O/c1-18-11-4-6-21(7-5-11)16-15-14(19-9-20-16)12-8-10(17)2-3-13(12)22-15/h2-3,8-9,11,18H,4-7H2,1H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Argenta Discovery Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after 2.5 hrs by scintillation proximity assay


Bioorg Med Chem Lett 20: 2516-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.097
BindingDB Entry DOI: 10.7270/Q2CN74V3
More data for this
Ligand-Target Pair