BDBM50315465 4,6-dihydroxy-2-((1-methyl-2-phenyl-1H-indol-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1090130

SMILES Cn1c(c(\C=C2/Oc3cc(O)cc(O)c3C2=O)c2ccccc12)-c1ccccc1

InChI Key InChIKey=CDRBGHJNUBPWFB-BKUYFWCQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315465   

LigandPNGBDBM50315465(4,6-dihydroxy-2-((1-methyl-2-phenyl-1H-indol-3-yl)...)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315465(4,6-dihydroxy-2-((1-methyl-2-phenyl-1H-indol-3-yl)...)
Affinity DataIC50:  96nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed