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BDBM50315510 3-(1'-(2,4-dichlorobenzyl)-2'-oxospiro[[1,3]dioxolane-2,3'-indoline]-7'-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide::CHEMBL1089115

SMILES: Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21OCCO1

InChI Key: InChIKey=NNEDDKWVADKNIV-FNORWQNLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315510   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50315510
PNG
(3-(1'-(2,4-dichlorobenzyl)-2'-oxospiro[[1,3]dioxol...)
Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21OCCO1
Show InChI InChI=1S/C24H16Cl4N2O6S2/c25-15-6-4-14(17(26)10-15)12-30-21-13(2-1-3-16(21)24(23(30)32)35-8-9-36-24)5-7-19(31)29-38(33,34)20-11-18(27)22(28)37-20/h1-7,10-11H,8-9,12H2,(H,29,31)/b7-5+
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a



deCODE Chemistry

Curated by ChEMBL


Assay Description
Displacement of [3H]PGE2 from human EP3 receptor in buffer


Bioorg Med Chem Lett 20: 2658-64 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.028
BindingDB Entry DOI: 10.7270/Q2668DCG
More data for this
Ligand-Target Pair