BDBM50315732 CHEMBL1092568::{3-[5-Methyl-4-morpholin-4-yl-7-(pyrrolidin-1-ylmethyl)-5Hpyrrolo[3,2-d]pyrimidin-2-yl]phenyl}methanol

SMILES Cn1cc(CN2CCCC2)c2nc(nc(N3CCOCC3)c12)-c1cccc(CO)c1

InChI Key InChIKey=ONUKOAFJMMCPRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315732   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315732BDBM50315732({3-[5-Methyl-4-morpholin-4-yl-7-(pyrrolidin-1-ylme...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50315732BDBM50315732({3-[5-Methyl-4-morpholin-4-yl-7-(pyrrolidin-1-ylme...)
Affinity DataIC50: 4.21E+3nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed