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BDBM50315876 (S)-N-(4-fluorobenzyl)-N-(2-(1-phenylethylamino)pyridin-4-yl)naphthalene-2-sulfonamide::CHEMBL1092348

SMILES: C[C@H](Nc1cc(ccn1)N(Cc1ccc(F)cc1)S(=O)(=O)c1ccc2ccccc2c1)c1ccccc1

InChI Key: InChIKey=VIRXXMFAHIWTKJ-ANBDAQEENA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315876   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50315876
PNG
((S)-N-(4-fluorobenzyl)-N-(2-(1-phenylethylamino)py...)
Show SMILES C[C@H](Nc1cc(ccn1)N(Cc1ccc(F)cc1)S(=O)(=O)c1ccc2ccccc2c1)c1ccccc1
Show InChI InChI=1/C30H26FN3O2S/c1-22(24-7-3-2-4-8-24)33-30-20-28(17-18-32-30)34(21-23-11-14-27(31)15-12-23)37(35,36)29-16-13-25-9-5-6-10-26(25)19-29/h2-20,22H,21H2,1H3,(H,32,33)/t22-/s2
PDB
MMDB

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UniProtKB/SwissProt
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DrugBank
GoogleScholar
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PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 7.54E+3n/an/an/an/an/an/a



Scios Inc

Curated by ChEMBL


Assay Description
Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counter


Bioorg Med Chem Lett 20: 2556-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.088
BindingDB Entry DOI: 10.7270/Q2VT1S84
More data for this
Ligand-Target Pair