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BDBM50316157 2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-(5-propylpyrimidin-2-yl)piperidin-4-yl]carbonyl}sulfamate::CHEMBL1093026

SMILES: CCCc1cnc(nc1)N1CCC(CC1)(C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C)c1cccc(OC)c1

InChI Key: InChIKey=IQWFXBLWVWKDMF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316157   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50316157
PNG
(2,6-Diisopropylphenyl{[4-(3-Methoxyphenyl)-1-(5-pr...)
Show SMILES CCCc1cnc(nc1)N1CCC(CC1)(C(=O)NS(=O)(=O)Oc1c(cccc1C(C)C)C(C)C)c1cccc(OC)c1
Show InChI InChI=1S/C32H42N4O5S/c1-7-10-24-20-33-31(34-21-24)36-17-15-32(16-18-36,25-11-8-12-26(19-25)40-6)30(37)35-42(38,39)41-29-27(22(2)3)13-9-14-28(29)23(4)5/h8-9,11-14,19-23H,7,10,15-18H2,1-6H3,(H,35,37)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat macrophages ACAT


J Med Chem 53: 3284-95 (2010)


Article DOI: 10.1021/jm901909p
BindingDB Entry DOI: 10.7270/Q2639PWV
More data for this
Ligand-Target Pair