BDBM50316486 CHEMBL1096491::N-(4-{4-[2-({[2-(Dimethylamino)ethyl]amino}methyl)-1Hpyrrolo[2,3-b]pyridin-4-yl]-1-ethyl-1H-pyrazol-3-yl}phenyl)-N'-phenylurea

SMILES CCn1cc(c(n1)-c1ccc(NC(=O)Nc2ccccc2)cc1)-c1ccnc2[nH]c(CNCCN(C)C)cc12

InChI Key InChIKey=DQJRSRINKOLTGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316486   

TargetAurora kinase A(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316486(CHEMBL1096491 | N-(4-{4-[2-({[2-(Dimethylamino)eth...)
Affinity DataIC50:  5.48E+3nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50316486(CHEMBL1096491 | N-(4-{4-[2-({[2-(Dimethylamino)eth...)
Affinity DataIC50:  276nMAssay Description:Inhibition of human Aurora B by rapid dilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed