BDBM50316704 CHEMBL1095522::N-[2-(7-{4-[3-(2-Acetylaminoethyl)-1H-indol-5-yloxy]-butoxy}-naphthalen-1-yl)ethyl]acetamide

SMILES CC(=O)NCCc1c[nH]c2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12

InChI Key InChIKey=GNQUIGRVFLTMRQ-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316704   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50316704(CHEMBL1095522 | N-[2-(7-{4-[3-(2-Acetylaminoethyl)...)
Affinity DataKi:  4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50316704(CHEMBL1095522 | N-[2-(7-{4-[3-(2-Acetylaminoethyl)...)
Affinity DataKi:  84nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50316704(CHEMBL1095522 | N-[2-(7-{4-[3-(2-Acetylaminoethyl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
University Of Lille

Curated by ChEMBL
LigandPNGBDBM50316704(CHEMBL1095522 | N-[2-(7-{4-[3-(2-Acetylaminoethyl)...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed