BDBM50317227 (E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(4-(4-ethylpiperazin-1-yl)but-1-enyl)-6-methoxyquinoline-3-carbonitrile::CHEMBL1087978
SMILES CCN1CCN(CC\C=C\c2cc3ncc(C#N)c(Nc4cc(OC)c(Cl)cc4Cl)c3cc2OC)CC1
InChI Key InChIKey=YSOWEAROBZXTGU-FNORWQNLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50317227
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair