BDBM50317230 (E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-((dimethylamino)methyl)pyridin-2-yl)vinyl)-6-methoxyquinoline-3-carbonitrile::CHEMBL1087216

SMILES COc1cc(Nc2c(cnc3cc(\C=C\c4cccc(CN(C)C)n4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=VWCDZGNJJXNGRD-CMDGGOBGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317230   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317230((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317230((E)-4-(2,4-dichloro-5-methoxyphenylamino)-7-(2-(6-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed