BDBM50317238 (E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-(11-morpholinoundec-1-enyl)quinoline-3-carbonitrile::CHEMBL1098363

SMILES COc1cc(Nc2c(cnc3cc(\C=C\CCCCCCCCCN4CCOCC4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=PYCPJIWELLKLKR-ZRDIBKRKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50317238   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317238((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Src-mediated cell proliferation in rat Rat-2 fibroblasts after 4 days by MTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50317238((E)-4-(2,4-dichloro-5-methoxyphenylamino)-6-methox...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed