BDBM50317326 CHEMBL1086932::N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-5-methyl-1-phenyl-1H-pyrazole-4-carboxamide

SMILES Cc1c(cnn1-c1ccccc1)C(=O)Nc1ccc(Oc2ccnc3cc(sc23)-c2cn(C)cn2)c(F)c1

InChI Key InChIKey=LKHSVIZPSAOZJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50317326   

TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317326(CHEMBL1086932 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  150nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317326(CHEMBL1086932 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317326(CHEMBL1086932 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  70nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed