BDBM41575 CHEMBL1094408::US8614220, A85B1C1Z

SMILES: COc1ccc(cc1Nc1ncc2CCc3c(nn(C)c3-c2n1)C(N)=O)N1CCN(C)CC1

InChI Key: InChIKey=SWTRIZHCIUWGAU-UHFFFAOYSA-N

Data: 39 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 41575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK2 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK3 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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STE20-like serine/threonine-protein kinase (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	355	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	587	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	219	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	3.0	n/a
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Hepatocyte growth factor receptor (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Nek6 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 4 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C beta type (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM41575 (CHEMBL1094408 | US8614220, A85B1C1Z) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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