BDBM50318168 CHEMBL1097368::N-1H-indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

SMILES C(Cc1ccccc1)c1cc2c(Nc3ccc4[nH]ccc4c3)ncnc2[nH]1

InChI Key InChIKey=PWLPHODRHOUKAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318168   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318168(CHEMBL1097368 | N-1H-indol-5-yl-6-(2-phenylethyl)-...)
Affinity DataIC50:  5.61E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318168(CHEMBL1097368 | N-1H-indol-5-yl-6-(2-phenylethyl)-...)
Affinity DataIC50:  1.04E+5nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318168(CHEMBL1097368 | N-1H-indol-5-yl-6-(2-phenylethyl)-...)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50318168(CHEMBL1097368 | N-1H-indol-5-yl-6-(2-phenylethyl)-...)
Affinity DataIC50:  2.24E+5nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed