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BDBM50318312 (R)-5-hexyl-3-phenyloxazolidin-2-one::CHEMBL1094762

SMILES: CCCCCC[C@@H]1CN(C(=O)O1)c1ccccc1

InChI Key: InChIKey=VSVXANNIGPUQAD-YQTOOIBONA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318312   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50318312
PNG
((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Show SMILES CCCCCC[C@@H]1CN(C(=O)O1)c1ccccc1
Show InChI InChI=1/C15H21NO2/c1-2-3-4-8-11-14-12-16(15(17)18-14)13-9-6-5-7-10-13/h5-7,9-10,14H,2-4,8,11-12H2,1H3/t14-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 450n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...


Bioorg Med Chem Lett 20: 3129-33 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.089
BindingDB Entry DOI: 10.7270/Q2Z038B7
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50318312
PNG
((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Show SMILES CCCCCC[C@@H]1CN(C(=O)O1)c1ccccc1
Show InChI InChI=1/C15H21NO2/c1-2-3-4-8-11-14-12-16(15(17)18-14)13-9-6-5-7-10-13/h5-7,9-10,14H,2-4,8,11-12H2,1H3/t14-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 590n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...


Bioorg Med Chem Lett 20: 3129-33 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.089
BindingDB Entry DOI: 10.7270/Q2Z038B7
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50318312
PNG
((R)-5-hexyl-3-phenyloxazolidin-2-one | CHEMBL10947...)
Show SMILES CCCCCC[C@@H]1CN(C(=O)O1)c1ccccc1
Show InChI InChI=1/C15H21NO2/c1-2-3-4-8-11-14-12-16(15(17)18-14)13-9-6-5-7-10-13/h5-7,9-10,14H,2-4,8,11-12H2,1H3/t14-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.38E+4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calcium f...


Bioorg Med Chem Lett 20: 3129-33 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.089
BindingDB Entry DOI: 10.7270/Q2Z038B7
More data for this
Ligand-Target Pair