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BDBM50318369 3-((2-oxo-3-phenyloxazolidin-5-yl)methoxy)benzamide::CHEMBL1097397

SMILES: NC(=O)c1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1

InChI Key: InChIKey=ZUNNHLGHFREVAS-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318369   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50318369
PNG
(3-((2-oxo-3-phenyloxazolidin-5-yl)methoxy)benzamid...)
Show SMILES NC(=O)c1cccc(OCC2CN(C(=O)O2)c2ccccc2)c1
Show InChI InChI=1S/C17H16N2O4/c18-16(20)12-5-4-8-14(9-12)22-11-15-10-19(17(21)23-15)13-6-2-1-3-7-13/h1-9,15H,10-11H2,(H2,18,20)
PDB

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Similars

Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Allosteric modulation of human mGluR2 expressed in CHO dhfr cells co-expressing G-protein Galpha16 assessed as potentiation of glutamate-induced calc...


Bioorg Med Chem Lett 20: 3129-33 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.089
BindingDB Entry DOI: 10.7270/Q2Z038B7
More data for this
Ligand-Target Pair