BDBM50318493 3-isopropyl 5-(2-methoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate::BAY-E-9736::CHEMBL1428::NIMODIPINE::Nimotop

SMILES: COCCOC(=O)C1=C(C)N=C(C)C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC(C)C

InChI Key: InChIKey=SVMHYHIZWOJKDL-UHFFFAOYSA-N

Data: 7 KI  1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50318493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Human)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Human)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Mouse)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Rat)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Rat)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Rat)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		2.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Rat)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Human)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		8.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rat)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rat)	BDBM50318493 (Nimotop | 3-isopropyl 5-(2-methoxyethyl) 2,6-dimet...) Show SMILES Show InChI	GoogleScholar	UniChem		4.43E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair