BDBM50318495 Bay k 8644::CHEMBL1082832::methyl 2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate

SMILES COC(=O)C1=C(C)N=C(C)C(C1c1ccccc1C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=HLQRHTWAVXFDBJ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318495   

LigandPNGBDBM50318495(Bay k 8644 | CHEMBL1082832 | methyl 2,6-dimethyl-5...)
Affinity DataKi:  1.11E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Mus musculus)
Ferrara University

Curated by ChEMBL
LigandPNGBDBM50318495(Bay k 8644 | CHEMBL1082832 | methyl 2,6-dimethyl-5...)
Affinity DataEC50:  3.27E+4nMAssay Description:Agonist activity at mouse TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed