BDBM50318564 (1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol-4-yl)methylamino)cyclohexane-1,2,3,4,5-pentaol::CHEMBL1084109

SMILES CCCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1

InChI Key InChIKey=BNEBWGRZFSZRAG-XLGNRPJKSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318564   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50318564((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)
Affinity DataKi:  60nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50318564((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)
Affinity DataIC50:  30nMpH: 5.2Assay Description:Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50318564((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)
Affinity DataIC50:  60nMpH: 7.4Assay Description:Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50318564((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)
Affinity DataIC50:  30.2nMAssay Description:Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed